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Brief treatment with heparin-binding EGF-like growth factor, but not with EGF, is sufficient to accelerate epithelial wound healing

BACKGROUND: Heparin-binding EGF-like growth factor (HB-EGF) contains, in contrast to EGF, a domain that binds to negatively charged glycans on cell surfaces and in extracellular matrix. We speculated that a short exposure to HB-EGF induces prolonged biological effects such as healing of wounds after...

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Autori principali: Tolino, Michael A., Block, Ethan R., Klarlund, Jes K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143286/
https://ncbi.nlm.nih.gov/pubmed/21640162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.05.011
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