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Two Mutations Impair the Stability and Function of Ubiquitin-Activating Enzyme (E1)

Protein ubiquitination plays critical roles in the regulation of multiple cellular processes including cell proliferation, signal transduction, oncogenesis and hypoxic response. TS20 is a Balb3T3-derived cell line in which ubiquitination is inhibited by restrictive temperature. While TS20 has been u...

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Autori principali: Lao, Taotao, Chen, Shuyang, Sang, Nianli
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184329/
https://ncbi.nlm.nih.gov/pubmed/21678405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22870
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