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Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain
Binding of erythropoietin (Epo) to the Epo receptor (EpoR) is crucial for production of mature red cells. Although it is well established that the Epo-bound EpoR is a dimer, it is not clear whether, in the absence of ligand, the intact EpoR is a monomer or oligomer. Using antibody-mediated immunoflu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31843/ https://ncbi.nlm.nih.gov/pubmed/11296286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081069198 |
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