Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

Oestrogen receptors α (ERα) are expressed in a subset of mammary epithelial cells. Here, the authors identify cells with low-ERα protein levels and show that distinct cell populations have distinct requirements for the AF1 and AF2 domains of the ERα, and ERα acts in a biphasic manner dependent on de...

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Detalhes bibliográficos

Principais autores:	Stéphanie Cagnet, Dalya Ataca, George Sflomos, Patrick Aouad, Sonia Schuepbach-Mallepell, Henry Hugues, Andrée Krust, Ayyakkannu Ayyanan, Valentina Scabia, Cathrin Brisken
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2018-11-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-018-07175-0
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