Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain

Binding of erythropoietin (Epo) to the Epo receptor (EpoR) is crucial for production of mature red cells. Although it is well established that the Epo-bound EpoR is a dimer, it is not clear whether, in the absence of ligand, the intact EpoR is a monomer or oligomer. Using antibody-mediated immunoflu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Constantinescu, Stefan N., Keren, Tzvia, Socolovsky, Merav, Nam, Hyung-song, Henis, Yoav I., Lodish, Harvey F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.081069198
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