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Copper-Free Sonogashira Cross-Coupling for Functionalization of Alkyne-Encoded Proteins in Aqueous Medium and in Bacterial Cells

Bioorthogonal reactions suitable for functionalization of genetically or metabolically encoded alkynes, e.g., copper-catalyzed azide-alkyne cycloaddition reaction (“click chemistry”), have provided chemical tools to study biomolecular dynamics and function in living systems. Despite its prominence i...

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Detalhes bibliográficos
Main Authors: Li, Nan, Lim, Reyna K. V., Edwardraja, Selvakumar, Lin, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184007/
https://ncbi.nlm.nih.gov/pubmed/21899368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2066913
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