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High-Throughput Analysis of Concentration-Dependent Antibody Self-Association

Monoclonal antibodies are typically monomeric and nonviscous at low concentrations, yet they display highly variable associative and viscous behavior at elevated concentrations. Although measurements of antibody self-association are critical for understanding this complex behavior, traditional bioph...

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Detalhes bibliográficos
Main Authors: Sule, Shantanu V., Sukumar, Muppalla, Weiss, William F., Marcelino-Cruz, Anna Marie, Sample, Tyler, Tessier, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183799/
https://ncbi.nlm.nih.gov/pubmed/21961601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.036
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