A role for intermolecular disulfide bonds in prion diseases?
The key event in prion diseases seems to be the conversion of the prion protein PrP from its normal cellular isoform (PrP(C)) to an aberrant “scrapie” isoform (PrP(Sc)). Earlier studies have detected no covalent modification in the scrapie isoform and have concluded that the PrP(C) → PrP(Sc) convers...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2001
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071066598 |
| टैग: |
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