Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids

Peptide nucleic acids (PNAs) bind duplex DNA in a sequence-specific manner, creating triplex structures that can provoke DNA repair and produce genome modification. CCR5 encodes a chemokine receptor required for HIV-1 entry into human cells and individuals carrying mutations in this gene are resista...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Schleifman, Erica B., Bindra, Ranjit, Leif, Jean, Campo, Jacob del, Rogers, Faye A., Uchil, Pradeep, Kutsch, Olaf, Shultz, Leonard D., Kumar, Priti, Greiner, Dale L., Glazer, Peter M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183429/
https://ncbi.nlm.nih.gov/pubmed/21944757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.010
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы