Anti-AIDS agents 86. Synthesis and anti-HIV evaluation of 2′,3′-seco-3′-nor DCP and DCK analogues

In a continuing study of novel anti-HIV agents with drug-like structures and properties, 30 1′-O-, 1′-S-, 4′-O- and 4′-substituted-2′,3′-seco-3′-nor DCP and DCK analogues (8–37) were designed and synthesized. All newly synthesized seco-compounds were screened against HIV-1(NL4-3) and a multiple reve...

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Main Authors: Chen, Ying, Cheng, Ming, Liu, Faqiang, Xia, Peng, Qian, Keduo, Yu, Donglei, Xia, Yi, Yang, Zheng-Yu, Chen, Chin-Ho, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183312/
https://ncbi.nlm.nih.gov/pubmed/21864952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.07.051
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