High Throughput Screening of a Library Based on Kinase Inhibitor Scaffolds Against Mycobacterium Tuberculosis H37Rv

Kinase targets are being pursued in a variety of diseases beyond cancer, including immune and metabolic as well as viral, parasitic, fungal and bacterial. In particular, there is a relatively recent interest in kinase and ATP-binding targets in Mycobacterium tuberculosis in order to identify inhibit...

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Hauptverfasser: Reynolds, Robert C., Ananthan, Subramaniam, Faaleolea, Ellen, Hobrath, Judith V., Kwong, Cecil D., Maddox, Clinton, Rasmussen, Lynn, Sosa, Melinda I., Thammasuvimol, Elizabeth, White, E. Lucile, Zhang, Wei, Secrist, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183257/
https://ncbi.nlm.nih.gov/pubmed/21708485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.05.005
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