A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice

Heterozygous Twirler (Tw) mice develop obesity and circling behavior associated with malformations of the inner ear, whereas homozygous Tw mice have cleft palate and die shortly after birth. Zeb1 is a zinc finger protein that contributes to mesenchymal cell fate by repression of genes whose expressi...

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Библиографические подробности
Главные авторы: Kurima, Kiyoto, Hertzano, Ronna, Gavrilova, Oksana, Monahan, Kelly, Shpargel, Karl B., Nadaraja, Garani, Kawashima, Yoshiyuki, Lee, Kyu Yup, Ito, Taku, Higashi, Yujiro, Eisenman, David J., Strome, Scott E., Griffith, Andrew J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183090/
https://ncbi.nlm.nih.gov/pubmed/21980308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002307
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