Systemic Fluorescent Gentamicin Enters Neonatal Mouse Hair Cells Predominantly Through Sensory Mechanoelectrical Transduction Channels

Systemically administered aminoglycoside antibiotics can enter inner ear hair cells and trigger apoptosis. However, the in vivo route(s) by which aminoglycoside antibiotics enter hair cells remains controversial. Aminoglycosides can enter mouse hair cells by endocytosis or by permeation through tran...

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Bibliografiske detaljer
Udgivet i:J Assoc Res Otolaryngol
Main Authors: Makabe, Ayane, Kawashima, Yoshiyuki, Sakamaki, Yuriko, Maruyama, Ayako, Fujikawa, Taro, Ito, Taku, Kurima, Kiyoto, Griffith, Andrew J., Tsutsumi, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270392/
https://ncbi.nlm.nih.gov/pubmed/32152768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-020-00746-3
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