Systemic Fluorescent Gentamicin Enters Neonatal Mouse Hair Cells Predominantly Through Sensory Mechanoelectrical Transduction Channels

Systemically administered aminoglycoside antibiotics can enter inner ear hair cells and trigger apoptosis. However, the in vivo route(s) by which aminoglycoside antibiotics enter hair cells remains controversial. Aminoglycosides can enter mouse hair cells by endocytosis or by permeation through tran...

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Bibliographic Details
Published in:J Assoc Res Otolaryngol
Main Authors: Makabe, Ayane, Kawashima, Yoshiyuki, Sakamaki, Yuriko, Maruyama, Ayako, Fujikawa, Taro, Ito, Taku, Kurima, Kiyoto, Griffith, Andrew J., Tsutsumi, Takeshi
Format: Artigo
Language:Inglês
Published: Springer US 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270392/
https://ncbi.nlm.nih.gov/pubmed/32152768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-020-00746-3
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