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Inter-Allelic Prion Propagation Reveals Conformational Relationships among a Multitude of [PSI] Strains

Immense diversity of prion strains is observed, but its underlying mechanism is less clear. Three [PSI] prion strains—named VH, VK, and VL—were previously isolated in the wild-type yeast genetic background. Here we report the generation and characterization of eight new [PSI] isolates, obtained by p...

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Autors principals: Lin, Jia-Yu, Liao, Tzu-Ya, Lee, Han-Chung, King, Chih-Yen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183073/
https://ncbi.nlm.nih.gov/pubmed/21980301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002297
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