ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing

Despite intense interest, methods that provide enhanced sensitivity and specificity in parallel measurements of candidate protein biomarkers in numerous samples have been lacking. We present herein a multiplex proximity ligation assay with readout via realtime PCR or DNA sequencing (ProteinSeq). We...

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Detalhes bibliográficos
Main Authors: Darmanis, Spyros, Nong, Rachel Yuan, Vänelid, Johan, Siegbahn, Agneta, Ericsson, Olle, Fredriksson, Simon, Bäcklin, Christofer, Gut, Marta, Heath, Simon, Gut, Ivo Glynne, Wallentin, Lars, Gustafsson, Mats G., Kamali-Moghaddam, Masood, Landegren, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183061/
https://ncbi.nlm.nih.gov/pubmed/21980495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025583
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