ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing

Despite intense interest, methods that provide enhanced sensitivity and specificity in parallel measurements of candidate protein biomarkers in numerous samples have been lacking. We present herein a multiplex proximity ligation assay with readout via realtime PCR or DNA sequencing (ProteinSeq). We...

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Hlavní autoři: Darmanis, Spyros, Nong, Rachel Yuan, Vänelid, Johan, Siegbahn, Agneta, Ericsson, Olle, Fredriksson, Simon, Bäcklin, Christofer, Gut, Marta, Heath, Simon, Gut, Ivo Glynne, Wallentin, Lars, Gustafsson, Mats G., Kamali-Moghaddam, Masood, Landegren, Ulf
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183061/
https://ncbi.nlm.nih.gov/pubmed/21980495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025583
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