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Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes

A change in chromosome number, known as aneuploidy, is a common characteristic of cancer. Aneuploidy disrupts gene expression in human cancer cells and immortalized human epithelial cells, but not in normal human cells. However, the relationship between aneuploidy and cancer remains unclear. To stud...

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Bibliografski detalji
Glavni autori: Nawata, Hisakatsu, Kashino, Genro, Tano, Keizo, Daino, Kazuhiro, Shimada, Yoshiya, Kugoh, Hiroyuki, Oshimura, Mitsuo, Watanabe, Masami
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183047/
https://ncbi.nlm.nih.gov/pubmed/21980425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025319
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