Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation

Heat shock response is characterized by the induction of heat shock proteins (HSPs), which facilitate protein folding, and non-HSP proteins with diverse functions, including protein degradation, and is regulated by heat shock factors (HSFs). HSF1 is a master regulator of HSP expression during heat s...

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Main Authors: Shinkawa, Toyohide, Tan, Ke, Fujimoto, Mitsuaki, Hayashida, Naoki, Yamamoto, Kaoru, Takaki, Eiichi, Takii, Ryosuke, Prakasam, Ramachandran, Inouye, Sachiye, Mezger, Valerie, Nakai, Akira
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183013/
https://ncbi.nlm.nih.gov/pubmed/21813737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0330
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