Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells

In antigen (Ag) cross-presentation, dendritic cells (DCs) take up extracellular Ag and translocate them from the endosome to the cytosol for proteasomal degradation. The processed peptides can enter the conventional MHC I pathway. The molecules responsible for the translocation of Ag across the endo...

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Bibliographische Detailangaben
Hauptverfasser: Imai, Takashi, Kato, Yu, Kajiwara, Chiaki, Mizukami, Shusaku, Ishige, Ikuo, Ichiyanagi, Tomoko, Hikida, Masaki, Wang, Ji-Yang, Udono, Heiichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182735/
https://ncbi.nlm.nih.gov/pubmed/21930907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108372108
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