Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

Primary tumors facilitate metastasis by directing bone marrow-derived cells (BMDCs) to colonize the lungs before the arrival of cancer cells. Here, we demonstrate that hypoxia-inducible factor 1 (HIF-1) is a critical regulator of breast cancer metastatic niche formation through induction of multiple...

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Detalhes bibliográficos
Main Authors: Wong, Carmen Chak-Lui, Gilkes, Daniele M., Zhang, Huafeng, Chen, Jasper, Wei, Hong, Chaturvedi, Pallavi, Fraley, Stephanie I., Wong, Chun-Ming, Khoo, Ui-Soon, Ng, Irene Oi-Lin, Wirtz, Denis, Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182724/
https://ncbi.nlm.nih.gov/pubmed/21911388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113483108
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