Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions and have emerged as promising therapeutic targets for such diseases as cancer and neurodegenerative disorders. Thus, small...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Jing, Du, Yuhong, Horton, John R., Upadhyay, Anup K., Lou, Bin, Bai, Yan, Zhang, Xing, Du, Lupei, Li, Minyong, Wang, Binghe, Zhang, Lixin, Barbieri, Joseph T., Khuri, Fadlo R., Cheng, Xiaodong, Fu, Haian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182712/
https://ncbi.nlm.nih.gov/pubmed/21908710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100012108
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