Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions and have emerged as promising therapeutic targets for such diseases as cancer and neurodegenerative disorders. Thus, small...

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Bibliografiset tiedot
Päätekijät: Zhao, Jing, Du, Yuhong, Horton, John R., Upadhyay, Anup K., Lou, Bin, Bai, Yan, Zhang, Xing, Du, Lupei, Li, Minyong, Wang, Binghe, Zhang, Lixin, Barbieri, Joseph T., Khuri, Fadlo R., Cheng, Xiaodong, Fu, Haian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182712/
https://ncbi.nlm.nih.gov/pubmed/21908710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100012108
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