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Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions and have emerged as promising therapeutic targets for such diseases as cancer and neurodegenerative disorders. Thus, small...

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Main Authors: Zhao, Jing, Du, Yuhong, Horton, John R., Upadhyay, Anup K., Lou, Bin, Bai, Yan, Zhang, Xing, Du, Lupei, Li, Minyong, Wang, Binghe, Zhang, Lixin, Barbieri, Joseph T., Khuri, Fadlo R., Cheng, Xiaodong, Fu, Haian
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182712/
https://ncbi.nlm.nih.gov/pubmed/21908710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100012108
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