Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions and have emerged as promising therapeutic targets for such diseases as cancer and neurodegenerative disorders. Thus, small...

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Detalhes bibliográficos
Main Authors: Zhao, Jing, Du, Yuhong, Horton, John R., Upadhyay, Anup K., Lou, Bin, Bai, Yan, Zhang, Xing, Du, Lupei, Li, Minyong, Wang, Binghe, Zhang, Lixin, Barbieri, Joseph T., Khuri, Fadlo R., Cheng, Xiaodong, Fu, Haian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182712/
https://ncbi.nlm.nih.gov/pubmed/21908710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100012108
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