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Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor
The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions and have emerged as promising therapeutic targets for such diseases as cancer and neurodegenerative disorders. Thus, small...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182712/ https://ncbi.nlm.nih.gov/pubmed/21908710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100012108 |
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