HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer

Prostate cancer (CaP) is the most common cancer among adult men in the Western world. Better insight into its tumor-activating pathways may facilitate the development of targeted therapies. In this study, we show that patients who develop prostate tumors with low levels of PTEN and high levels of HE...

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Hlavní autoři: Ahmad, Imran, Patel, Rachana, Singh, Lukram Babloo, Nixon, Colin, Seywright, Morag, Barnetson, Robert J., Brunton, Valerie G., Muller, William J., Edwards, Joanne, Sansom, Owen J., Leung, Hing Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182686/
https://ncbi.nlm.nih.gov/pubmed/21930937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101263108
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