Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines

Vaccine production and initiation of mass vaccination is a key factor in rapid response to new influenza pandemic. During the 2009–2010 H1N1 pandemic, several bottlenecks were identified, including the delayed availability of vaccine potency reagents. Currently, antisera for the single-radial immuno...

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Detalhes bibliográficos
Main Authors: Khurana, Surender, Larkin, Christopher, Verma, Swati, Joshi, Manju B., Fontana, Juan, Steven, Alasdair C., King, Lisa R., Manischewitz, Jody, McCormick, William, Gupta, Rajesh K., Golding, Hana
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182405/
https://ncbi.nlm.nih.gov/pubmed/21704111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.06.014
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