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Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus

BACKGROUND: In the face of impending influenza pandemic, a rapid vaccine production and mass vaccination is the most effective approach to prevent the large scale mortality and morbidity that was associated with the 1918 “Spanish Flu”. The traditional process of influenza vaccine production in eggs...

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Bibliographic Details
Main Authors: Khurana, Surender, Verma, Swati, Verma, Nitin, Crevar, Corey J., Carter, Donald M., Manischewitz, Jody, King, Lisa R., Ross, Ted M., Golding, Hana
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902520/
https://ncbi.nlm.nih.gov/pubmed/20634959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011548
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