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Kv7 Channels Can Function without Constitutive Calmodulin Tethering

M-channels are voltage-gated potassium channels composed of Kv7.2-7.5 subunits that serve as important regulators of neuronal excitability. Calmodulin binding is required for Kv7 channel function and mutations in Kv7.2 that disrupt calmodulin binding cause Benign Familial Neonatal Convulsions (BFNC)...

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Bibliografiske detaljer
Main Authors: Gómez-Posada, Juan Camilo, Aivar, Paloma, Alberdi, Araitz, Alaimo, Alessandro, Etxeberría, Ainhoa, Fernández-Orth, Juncal, Zamalloa, Teresa, Roura-Ferrer, Meritxell, Villace, Patricia, Areso, Pilar, Casis, Oscar, Villarroel, Alvaro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182250/
https://ncbi.nlm.nih.gov/pubmed/21980481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025508
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