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CRLX101 (formerly IT-101)–A Novel Nanopharmaceutical of Camptothecin in Clinical Development

CRLX101 (formerly IT-101) is a first-in-class nanopharmaceutical, currently in Phase 2a development, which has been developed by covalently conjugating camptothecin (CPT) to a linear, cyclodextrin-polyethylene glycol (CD-PEG) co-polymer that self-assembles into nanoparticles. As a nanometer-scale dr...

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Bibliographic Details
Main Authors: Young, Cissy, Schluep, Thomas, Hwang, Jungyeon, Eliasof, Scott
Format: Artigo
Language:Inglês
Published: Bentham Science Publishers Ltd 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182091/
https://ncbi.nlm.nih.gov/pubmed/22081768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157340711795163866
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