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Inhibition of the inflammasome response by a viral protein that interacts with NLRs

Pattern recognition receptors (PRRs) constitute the first line of host defense against bacterial, fungal and viral pathogens. Upon sensing microbial infection, PRRs initiate a cascade of signal transduction and transcriptional events to induce the production of inflammatory cytokines. As a result, m...

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Detalhes bibliográficos
Main Authors: Gregory, Sean M, Damania, Blossom
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181509/
https://ncbi.nlm.nih.gov/pubmed/21966559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.4.4.15252
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