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Temporal Smad7 Transgene Induction in Mouse Epidermis Accelerates Skin Wound Healing

The expression of Smad7, a tumor growth factor-β (TGFβ) antagonist, is increased during cutaneous wound healing. To assess this significance, we temporally induced Smad7 transgene expression in wounded skin in gene-switch-Smad7 transgenic (Smad7 tg) mice. Smad7 induction in epidermal keratinocytes c...

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書目詳細資料
Main Authors: Han, Gangwen, Li, Fulun, ten Dijke, Peter, Wang, Xiao-Jing
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181395/
https://ncbi.nlm.nih.gov/pubmed/21944279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.003
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