Tumor Necrosis Factor α-Converting Enzyme Inhibition Reverses Hepatic Steatosis and Improves Insulin Sensitivity Markers and Surgical Outcome in Mice

BACKGROUND: Hepatic steatosis is an established risk factor for complications following major hepatic resection. Pharmacological options to reverse steatosis prior to surgery, however, are lacking. We hypothesized that treatment with the pharmacologic tumor necrosis factor-α converting enzyme (TACE)...

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Bibliografiska uppgifter
Huvudupphovsmän: de Meijer, Vincent E., Le, Hau D., Meisel, Jonathan A., Sharma, Anisha K., Popov, Yury, Puder, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181348/
https://ncbi.nlm.nih.gov/pubmed/21980496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025587
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