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Targeted delivery of doxorubicin-utilizing chitosan nanoparticles surface-functionalized with anti-Her2 trastuzumab

BACKGROUND: Targeting drugs to their sites of action to overcome the systemic side effects associated with most antineoplastic agents is still a major challenge in pharmaceutical research. In this study, the monoclonal antibody, trastuzumab, was used as a targeting agent in nanoparticles carrying th...

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Detalhes bibliográficos
Main Authors: Yousefpour, Parisa, Atyabi, Fatemeh, Vasheghani-Farahani, Ebrahim, Movahedi, Ali-Akbar Mousavi, Dinarvand, Rassoul
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181058/
https://ncbi.nlm.nih.gov/pubmed/21976974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S21523
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