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Thiolated chitosan nanoparticles as a delivery system for antisense therapy: evaluation against EGFR in T47D breast cancer cells

Thiolated chitosan has high transfection and mucoadhesive properties. We investigated the potential of two recently synthesized polymers: NAC-C (N-acetyl cysteine-chitosan) and NAP-C (N-acetyl penicillamine-chitosan) in anticancer drug delivery targeting epidermal growth factor receptor (EGFR). Doxo...

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Autors principals: Talaei, Fatemeh, Azizi, Ebrahim, Dinarvand, Rassoul, Atyabi, Fatemeh
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181057/
https://ncbi.nlm.nih.gov/pubmed/21976973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S22731
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