Enhanced Oral Delivery of Docetaxel Using Thiolated Chitosan Nanoparticles: Preparation, In Vitro and In Vivo Studies

The aim of this study was to evaluate a nanoparticulate system with mucoadhesion properties composed of a core of polymethyl methacrylate surrounded by a shell of thiolated chitosan (Ch-GSH-pMMA) for enhancing oral bioavailability of docetaxel (DTX), an anticancer drug. DTX-loaded nanoparticles were...

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Detalhes bibliográficos
Main Authors: Saremi, Shahrooz, Dinarvand, Rassoul, Kebriaeezadeh, Abbas, Ostad, Seyed Nasser, Atyabi, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736506/
https://ncbi.nlm.nih.gov/pubmed/23971023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/150478
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