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Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells
BACKGROUND: Multidrug resistance remains a major obstacle to successful cancer chemotherapy. Some chemical multidrug resistance inhibitors, such as ciclosporin and verapamil, have been reported to reverse resistance in tumor cells. However, the accompanying side effects have limited their clinical a...
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主要な著者: | , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Dove Medical Press
2011
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3181056/ https://ncbi.nlm.nih.gov/pubmed/21976972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S23099 |
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