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Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model

We describe the evaluation of doxorubicin-loaded PEG-PE micelles targeting using an ovarian cancer cell spheroid model. Most ovarian cancer patients present at an advanced clinical stage and develop resistance to standard of care platinum/taxane therapy. Doxorubicin is also approved for ovarian canc...

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Hlavní autoři: Perche, Federico, Torchilin, Vladimir P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502646/
https://ncbi.nlm.nih.gov/pubmed/22974689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.09.003
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