Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells

BACKGROUND: Multidrug resistance remains a major obstacle to successful cancer chemotherapy. Some chemical multidrug resistance inhibitors, such as ciclosporin and verapamil, have been reported to reverse resistance in tumor cells. However, the accompanying side effects have limited their clinical a...

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Detalhes bibliográficos
Main Authors: Diao, Yuan-Yuan, Li, Hao-Ying, Fu, Ying-Hua, Han, Min, Hu, Yu-Lan, Jiang, Hong-Liang, Tsutsumi, Yasuo, Wei, Qi-Chun, Chen, Da-Wei, Gao, Jian-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181056/
https://ncbi.nlm.nih.gov/pubmed/21976972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S23099
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