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Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription.

ps- and aps-alpha anomeric oligodeoxyribonucleotides were designed to recognize in parallel (ps) or antiparallel (aps) orientation two different sites of a 1000 base-long mRNA. Northern blots experiments indicate that only ps-alpha-oligonucleotides were able to hybridize to the mRNA target. Furtherm...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Gagnor, C, Rayner, B, Leonetti, J P, Imbach, J L, Lebleu, B
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1989
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318098/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2474793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.13.5107
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