Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription.

ps- and aps-alpha anomeric oligodeoxyribonucleotides were designed to recognize in parallel (ps) or antiparallel (aps) orientation two different sites of a 1000 base-long mRNA. Northern blots experiments indicate that only ps-alpha-oligonucleotides were able to hybridize to the mRNA target. Furtherm...

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Main Authors: Gagnor, C, Rayner, B, Leonetti, J P, Imbach, J L, Lebleu, B
Format: Artigo
Jezik:Inglês
Izdano: 1989
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC318098/
https://ncbi.nlm.nih.gov/pubmed/2474793
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