Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding.

A new set of molecules made of an intercalating agent (oxazolopyridocarbazole, OPC) covalently linked through a polymethylene chain of various length to the 3' end of alpha-anomeric or beta-anomeric tetradeoxynucleotides (alpha- or beta-T4) have been synthesized. The beta-thymidylate modified c...

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Bibliographic Details
Main Authors: Gautier, C, Morvan, F, Rayner, B, Huynh-Dinh, T, Igolen, J, Imbach, J L, Paoletti, C, Paoletti, J
Format: Artigo
Language:Inglês
Published: 1987
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC306127/
https://ncbi.nlm.nih.gov/pubmed/3628001
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