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Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding.

A new set of molecules made of an intercalating agent (oxazolopyridocarbazole, OPC) covalently linked through a polymethylene chain of various length to the 3' end of alpha-anomeric or beta-anomeric tetradeoxynucleotides (alpha- or beta-T4) have been synthesized. The beta-thymidylate modified compou...

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Udgivet i:Nucleic Acids Res
Principais autores: Gautier, C, Morvan, F, Rayner, B, Huynh-Dinh, T, Igolen, J, Imbach, J L, Paoletti, C, Paoletti, J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1987
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3628001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.16.6625
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