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A Total Synthesis of OSW-1

A new and practical method was developed to synthesize OSW-1, a natural saponin with potent antitumor activities, from (+)-dehydroisoandrosterone, l-arabinose and d-xylose on gram scale. The synthesis was achieved in 10 linear steps with an overall yield of 6.4% starting from (+)-dehydroisoandroster...

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Bibliografische gegevens
Hoofdauteurs: Xue, Jie, Liu, Peng, Pan, Yanbin, Guo, Zhongwu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180821/
https://ncbi.nlm.nih.gov/pubmed/18067313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo7018812
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