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Total Synthesis of a Glycosylphosphatidylinositol Anchor of the Human Lymphocyte CD52 Antigen

The first total synthesis of a glycosylphosphatidylinositol (GPI) anchor bearing a polyunsaturated arachidonoyl fatty acid is reported. This lipid is found in mammalian GPIs that do not undergo lipid remodeling, a process that has important implications in the localization and function of GPI-anchor...

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Bibliografiske detaljer
Main Authors: Burgula, Srinivas, Swarts, Benjamin M., Guo, Zhongwu
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312375/
https://ncbi.nlm.nih.gov/pubmed/22189835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201102545
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