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Chemoenzymatic Synthesis of Glycosylphosphatidylinositol-Anchored Glycopeptides
MUC1 glycopeptide was efficiently coupled to glycosylphosphatidylinositol (GPI) derivatives by sortase A (SrtA), verifying that SrtA can accept sterically hindered glycopeptide as substrate for ligation with GPIs. This work has established a practical method for the chemoenzymatic synthesis of GPI-l...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166627/ https://ncbi.nlm.nih.gov/pubmed/20574591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc00828a |
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