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Sortase A-Catalyzed Peptide Cyclization for the Synthesis of Macrocyclic Peptides and Glycopeptides(,)

A chemoenzymatic method was developed for the synthesis of macrocyclic peptides and glycopeptides. Sortase A was found to mediate either head to tail cyclization or oligomerization and then head to tail cyclization of peptides and glycopeptides, depending on the peptide length, to produce 15-mer or...

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Sonraí Bibleagrafaíochta
Main Authors: Wu, Zhimeng, Guo, Xueqing, Guo, Zhongwu
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174090/
https://ncbi.nlm.nih.gov/pubmed/21738926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc13322e
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