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Sortase A-Catalyzed Peptide Cyclization for the Synthesis of Macrocyclic Peptides and Glycopeptides(,)

A chemoenzymatic method was developed for the synthesis of macrocyclic peptides and glycopeptides. Sortase A was found to mediate either head to tail cyclization or oligomerization and then head to tail cyclization of peptides and glycopeptides, depending on the peptide length, to produce 15-mer or...

詳細記述

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書誌詳細
主要な著者: Wu, Zhimeng, Guo, Xueqing, Guo, Zhongwu
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174090/
https://ncbi.nlm.nih.gov/pubmed/21738926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc13322e
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