Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan

BACKGROUND: Pyrazinamide (PZA) is an important first-line drug in multidrug-resistant tuberculosis (MDRTB) treatment. However, the unreliable results obtained from traditional susceptibility testing limits its usefulness in clinical settings. The detection of pncA gene mutations is a potential surro...

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Bibliographic Details
Main Authors: Chiu, Yu-Chi, Huang , Shiang-Fen, Yu, Kwok-Woon, Lee, Yu-Chin, Feng, Jia-Yih, Su, Wei-Juin
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180675/
https://ncbi.nlm.nih.gov/pubmed/21910892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-11-240
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