Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation

PURPOSE: Recent reports indicate that refractory central nervous system (CNS) metastases of non-small cell lung cancer (NSCLC) are improved by high-dose gefitinib or erlotinib administration. We describe a Japanese woman with NSCLC and CNS metastases who was resistant to 75 mg daily erlotinib, but t...

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Bibliografiske detaljer
Main Authors: Togashi, Yosuke, Masago, Katsuhiro, Fukudo, Masahide, Tsuchido, Yasuhiro, Okuda, Chiyuki, Kim, Young Hak, Ikemi, Yasuaki, Sakamori, Yuichi, Mio, Tadashi, Katsura, Toshiya, Mishima, Michiaki
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180562/
https://ncbi.nlm.nih.gov/pubmed/21681573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1691-z
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