Good Clinical Response to Erlotinib in a Non-Small Cell Lung Cancer Patient Harboring Multiple Brain Metastases and a Double Active Somatic Epidermal Growth Factor Gene Mutation

Recently, 2 small molecule kinase inhibitors (TKIs), targeting epidermal growth factor receptor (EGFR), have proven effective in the treatment of non-small cell lung cancer. However, it is unknown whether the EGFR double activating mutation of L858R in exon 21 and the in-frame deletion in exon 19 is...

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Main Authors: Masago, Katsuhiro, Togashi, Yosuke, Fukudo, Masahide, Terada, Tomohiro, Irisa, Kaoru, Sakamori, Yuichi, Fujita, Shiro, Kim, Young Hak, Mio, Tadashi, Inui, Ken-ichi, Mishima, Michiaki
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2010
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Published: April 2010
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919984/
https://ncbi.nlm.nih.gov/pubmed/20740181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000310830
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