EGFR mutation: Significance as a stratification factor in the era of molecular-targeted therapy

Somatic mutations of epidermal growth factor receptor (EGFR) are the strongest predictive markers for the response to EGFR-tyrosine kinase inhibitors (TKIs). Patients with EGFR mutations generally receive EGFR-TKI treatment, and their survival has been significantly improved compared with that befor...

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Main Authors: KIM, YOUNG HAK, MASAGO, KATSUHIRO, TOGASHI, YOSUKE, SAKAMORI, YUICHI, OKUDA, CHIYUKI, MIO, TADASHI, MISHIMA, MICHIAKI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410597/
https://ncbi.nlm.nih.gov/pubmed/22866092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.240
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