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Labelling oligonucleotides to high specific activity (I).

The normal procedure for labelling oligonucleotides radioactively is the use of polynucleotide kinase and gamma 32P-ATP. However, this has the disadvantage of only introducing one labelled base per molecule of the oligonucleotide. In this paper we describe an approach based on primer/template combin...

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Bibliographic Details
Main Authors: Craig, A G, Nizetic, D, Lehrach, H
Format: Artigo
Language:Inglês
Published: 1989
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC318018/
https://ncbi.nlm.nih.gov/pubmed/2526319
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